Filipa Brito

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Papers by Filipa Brito

Digital health and patient adherence: A qualitative study in older adults

DIGITAL HEALTH, Dec 31, 2023

Digital Therapeutics Evolution What kind of Research Will Make the Difference in this Area?

Adjunct Proceedings of the 2023 ACM International Joint Conference on Pervasive and Ubiquitous Computing & the 2023 ACM International Symposium on Wearable Computing

As in prescribable medical drug-based therapies, Digital Therapeutics (DTx) solutions introduce t... more As in prescribable medical drug-based therapies, Digital Therapeutics (DTx) solutions introduce the use of software as 1) an active ingredient implemented as digital interventions to improve patients' condition; and 2) as the excipient through which the intervention is conveyed to the patient. The most common DTx solutions implemented until today deal with the use of software-based solutions for dealing with mental health conditions. However, the potential of DTx is envisioned to grow to treat other health conditions with a number of technologies that still have not been duly explored. The objective of this workshop is to discuss the opportunities, barriers, and challenges of future DTx, the envisioned future use-cases, and the technologies with high potential to drive the uptake of these technologies, and this way to position this field as a solid complement of today's therapeutic approaches for dealing with different health conditions. • Interaction techniques; • ubiquitous and mobile devices; • design and evaluation methods;

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Digital Therapeutics with Virtual Reality and Sensors

Adjunct Proceedings of the 2023 ACM International Joint Conference on Pervasive and Ubiquitous Computing & the 2023 ACM International Symposium on Wearable Computing

Digital Therapeutics (DTx) is an emerging field within Digital Health that is rapidly growing and... more Digital Therapeutics (DTx) is an emerging field within Digital Health that is rapidly growing and holds promise for addressing anxiety-related disorders. Moreover, the combination of virtual reality (VR) and wearable sensors holds great potential for developing affordable, accessible, and effective DTx solutions. In this paper, we present our conception of a fully customised DTx for managing and supporting anxiety-related disorders therapy. We highlight five key assumptions that should be considered when developing such a DTx. These assumptions include the customisation of virtual environments (VEs); integration of physiological data and patient feedback; the use of dashboards for data visualisation; session replay and identification of peak response moments; and patient empowerment throughout the therapeutic process. By embracing these assumptions, we describe the main components constituting this DTx and emphasise fundamental features to fulfil the identified assumptions. Furthermore, we explore some of the potential benefits and challenges of DTx applied to mental health.

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Screening Mild Cognitive Impairment in Older Adults via Meaningful Play

With our rapid aging society, more and more people are suffering from dementia. This increase put... more With our rapid aging society, more and more people are suffering from dementia. This increase puts a great strain on the healthcare sector, as well in cost as manpower. This calls for research of reliable and regular assessments that can screen for Mild Cognitive Impairment (MCI), the precursor to dementia. We see that this call is answered with more and more cognitive screening games being developed. However, most of these games are based on existing tests, often lacking in adherence and enticing gameplay. This paper discusses the possibilities of meaningful play, and more specifically, Klondike Solitaire, as a cognitive screening test. We report on the results of an analysis of player actions in Solitaire with 3 health professionals that are experts in the domain of MCI. Results suggest that Klondike Solitaire can be used for such an assessment, and that this would be a valuable additional tool for longitudinal assessment.status: publishe

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Do we know what really works? A systematic review about using video games for cognitive training

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A meta-analysis of video games to promote cognition and functional capacity in MCI/dementia patients

This is the search protocol of a systematic review and meta-analysis regarding the efficacy of vi... more This is the search protocol of a systematic review and meta-analysis regarding the efficacy of video games as therapeutic tools to promote cognitive and functional capacity outcomes in patients with mild cognitive impairment/ dementia. PRISMA statement was used as guideline to develop the present protocol.

Confirmatory Factor Analysis of Sleep Model’s Questionnaires

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Designing Personalized Therapy Tools for People with Dementia

Proceedings of the 16th International Web for All Conference, 2019

Non-pharmacological interventions for people with dementia beneft from the usage of personalized ... more Non-pharmacological interventions for people with dementia beneft from the usage of personalized materials. These are not always easy to obtain. In a set of formative studies, we looked at how clinical staf and families recur to the usage of biographical elements to stimulate and foster the self-identity of people with dementia. Results showed that these stakeholders cherish biographically-rich information although it is often hard to obtain relevant materials. We present the iterative design of Scrapbook, a web platform that supports psychologists in the process of collecting meaningful information about a person, and applying it in reminiscence and cognitive stimulation sessions. A 3-phase deployment in a clinical setting allowed us to evolve the platform to respond to stakeholder requirements. Findings include a positive view of the developed features (e.g., biography-enriched games, caregiver app, group therapy) but also an underwhelming usage of the platform. We discuss the adoption, usage patterns, and feedback collected from clinicians, seeking to inform the design of personalized, i.e. biographically-rich, tools for therapy settings. CCS Concepts • Human-centered computing → Empirical studies in interaction design; Accessibility technologies.

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myView: End-user Authoring of Virtual Environments for Therapy

The 23rd International ACM SIGACCESS Conference on Computers and Accessibility, 2021

Virtual environments for therapy are scarce and lack personalization. The creation of these envir... more Virtual environments for therapy are scarce and lack personalization. The creation of these environments is done by specialists, is time-consuming, and expensive. We present a smartphone tool that allows non-specialists to create navigable virtual environments by taking and linking sequences of panoramic photo spheres, analogly to Google Street View. Editing the environments is then possible in a web platform, myView, where text, images, videos, sounds, and pick-up objects can be added. myView allows users to navigate their environments as well as sharing those environments with others. In a preliminary study with two psychologists, where myView was used as an elicitation probe, the approach was found to be useful for creating meaningful activities for reminiscence and cognitive training. The platform showed to be promising in the democratization of the crafting of virtual environments. • Human-centered computing → User studies.

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Enabling Biographical Cognitive Stimulation for People with Dementia

Extended Abstracts of the 2018 CHI Conference on Human Factors in Computing Systems, 2018

Non-pharmacological interventions are the most common and arguably most effective for people with... more Non-pharmacological interventions are the most common and arguably most effective for people with dementia. Some of these approaches have been proven to benefit from the usage of biographical or personalized materials. These contents are not always easy to obtain. Alongside, it is a challenge to maintain awareness of what is meaningful for a certain person. Faced with an absence of tools to collect and manage biographical materials, we created a web platform that supports the work of psychologists, streamlining the collection of relevant information about people with dementia. This knowledge is then used as a starting point to perform reminiscence and other biographical cognitive stimulation practices. In this paper, we present the design of our platform and results from a case study with one psychologist and three patients, across a period of two weeks that showed improvements in the collection of meaningful data about a person, and on maintaining awareness of the therapy as a whole.

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Can Card Games Be Used to Assess Mild Cognitive Impairment?

Extended Abstracts Publication of the Annual Symposium on Computer-Human Interaction in Play, 2017

This paper investigates whether Klondike Solitaire can be used as an assessment tool for mild cog... more This paper investigates whether Klondike Solitaire can be used as an assessment tool for mild cognitive impairment (MCI). It does so by providing a structured analysis and mapping player actions to cognitive functions. For Klondike Solitaire, 22 player actions were defined and mapped to 10 cognitive functions by 3 health professionals in the field of MCI. The results indicate that Attention, Executive Function, Object Recognition, Abstraction and Memory can be assessed through gameplay of Solitaire. Healthcare professionals confirmed that this can potentially be valuable, as it can screen for cognitive impairments longitudinally, in a nonintrusive way, without practice effects.

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Are Video Games Effective to Promote Cognition and Everyday Functional Capacity in Mild Cognitive Impairment/Dementia Patients? A Meta-Analysis of Randomized Controlled Trials

Journal of Alzheimer's Disease, 2021

Background: Mild cognitive impairment (MCI) and dementia are associated with increased age. MCI i... more Background: Mild cognitive impairment (MCI) and dementia are associated with increased age. MCI is a clinical entity described as a transitional state between normal cognition and dementia. Video games (VGs) can potentially promote cognition and functional capacity since multiple cognitive domains are recruited during gameplay. However, there is still a lack of consensus regarding the efficacy of VGs as therapeutic tools, particularly in neurodegenerative diseases. Objective: We aimed to analyze the impact of VGs on cognition and functional capacity outcomes in MCI/dementia patients. Methods: We conducted a systematic review and meta-analysis study (PROSPERO [CRD42021229445]). PubMed, Web of Science, Epistemonikos, CENTRAL, and EBSCO electronic databases were searched for RCT (2000-2021) that analyzed the impact of VGs on cognitive and functional capacity outcomes in MCI/dementia patients. Results: Nine studies were included (n = 409 participants), and Risk of Bias (RoB2) and qualit...

Dissecting Digital Card Games to Yield Digital Biomarkers for the Assessment of Mild Cognitive Impairment: Methodological Approach and Exploratory Study

JMIR Serious Games, 2021

BackgroundMild cognitive impairment (MCI), the intermediate cognitive status between normal cogni... more BackgroundMild cognitive impairment (MCI), the intermediate cognitive status between normal cognitive decline and pathological decline, is an important clinical construct for signaling possible prodromes of dementia. However, this condition is underdiagnosed. To assist monitoring and screening, digital biomarkers derived from commercial off-the-shelf video games may be of interest. These games maintain player engagement over a longer period of time and support longitudinal measurements of cognitive performance.ObjectiveThis paper aims to explore how the player actions of Klondike Solitaire relate to cognitive functions and to what extent the digital biomarkers derived from these player actions are indicative of MCI.MethodsFirst, 11 experts in the domain of cognitive impairments were asked to correlate 21 player actions to 11 cognitive functions. Expert agreement was verified through intraclass correlation, based on a 2-way, fully crossed design with type consistency. On the basis of...

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O sono e as funções executivas : O funcionamento executivo em sujeitos em privação crónica de sono após descanso e após um turno noturno

Pela sua finalidade académica, uma dissertação de mestrado é um trabalho individual, fruto do esf... more Pela sua finalidade académica, uma dissertação de mestrado é um trabalho individual, fruto do esforço e investimento pessoal. Contudo, importa realçar que a concretização deste projeto foi apenas possível graças à confluência do esforço e dedicação de várias pessoas, sendo agora imperativo dividir esta vitória com todos os que contribuíram de forma direta ou indireta para a concretização e conclusão deste trabalho. As minhas primeiras palavras de agradecimento têm que ser dirigidas forçosamente, aos meus pais. A eles, muito obrigada por todo o apoio sem o qual possivelmente não estaria aqui. Quero também agradecer a eles, o facto de me terem apoiado em todas as minhas escolhas de vida e pelo sentimento de responsabilidade e de trabalho árduo que desde sempre me incutiram. Dirijo agora as minhas palavras de agradecimento ao Prof. Doutor Alexandre Castro-Caldas, pela orientação, aconselhamento e partilha de conhecimento e experiência. Um muito obrigada a todos os docentes do Instituto de Ciências da Saúde da Universidade Católica de Lisboa, em especial à Professora Dra. Maria Vânia Nunes e ao Professor Manuel Luís Capelas pela sua compreensão e disponibilidade mesmo em tempo de férias. Gostaria também de agradecer de forma sincera o acolhimento e receção calorosa com que fui recebida no Hospital da Luz pelo Prof. Doutor José Roquette e

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An Expert Consensus Study on the Validity of Card Games to Assess Mild Cognitive Impairment (Preprint)

BACKGROUND Mild Cognitive Impairment, the intermediate cognitive status between healthy cognitive... more BACKGROUND Mild Cognitive Impairment, the intermediate cognitive status between healthy cognitive decline and pathological decline, is an important clinical construct for signaling possible prodromes of dementia. Unfortunately, there is an underdetection of this condition. To provide monitoring and screening, commercial off-the-shelf video games may be of interest. They maintain player engagement over a longer period of time and support longitudinal measurements of cognitive performance. OBJECTIVE This paper aims to explore how player actions of Klondike Solitaire relate to cognitive functions and to which extent they are indicative of Mild Cognitive Impairment. METHODS Eleven experts in the domain of cognitive impairments were asked to correlate 21 player actions to eleven cognitive functions. Expert agreement was verified through intraclass correlation, based on a two-way fully crossed design with type consistency. RESULTS All intraclass correlations for player actions and cogniti...

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