Martin Grossel

簡単なフェロセニル‐およびルテノセニル‐置換アザ‐クラウンエーテルのアルカリ金属との結合の性質

Journal of The Chemical Society-dalton Transactions, 1997

Optimisation of Polymer Scaffolds for Ocular Cell Transplantation

Investigative Ophthalmology & Visual Science, Apr 28, 2009

... ePrint ID: 181039. Deposited By: Dr Heather Thomson. Deposited On: 15 Apr 2011 09:24. Last Mo... more

ChemInform Abstract: Some Dinuclear and Trinuclear Platinum(II) Complexes of Bis(diphenylphosphinomethyl)phenylphosphine. A Novel Fluxional Process for cis-((Bis(bis(diphenylphosphinomethyl)phenylphosphine)dichloroplatinum(II))dichloroplatinum(II)), cis-(

ChemInform, Feb 20, 1990

ChemInform Abstract: MECHANISMS OF A-FRAME INVERSION FOR BINUCLEAR PLATINUM(II) COMPLEXES WITH BIS(DIPHENYLPHOSPHINO)METHANE LIGANDS

Chemischer Informationsdienst, Nov 22, 1983

ChemInform Abstract: CONFORMATIONAL STUDIES OF DIHYDROTETRAPHENYLMETHANES. I. X-RAY CRYSTALLOGRAPHIC AND SOLUTION HYDROGEN-1 NMR STUDIES OF TRANS-1,4-DIHYDRO-4-TRITYLBIPHENYL AND ITS 4′-BROMO DERIVATIVES: BOAT-BOAT INVERSION IN A CONGESTED CYCLOHEXA-1,4-D

Chemischer Informationsdienst, Dec 15, 1981

Im Gegensatz zum Bromderivat der Titelverbindung, das in zwei kristallinen Modifikationen auftrit... more

ChemInform Abstract: ACETOLYSE VON 2-(2,3-DIHYDRO-1H-CYCLOPENTA(L)-PHENANTHRENYL-(2))-AETHYL-DERIVATEN, TEILNAHME DER 9,10-BINDUNG DES PHENANTHRENS BEI DER DARST. EINES ANALOGEN DES KLASSISCHEN NORBORNYL-KATIONS

Chemischer Informationsdienst, Jun 27, 1972

Ausgehend von 9,10‐Phenanthrenchinon erhält man nach bekanntem Verfahren das Bromid (I), das bei ... more

ChemInform Abstract: Tris-μ-(bis(diphenylphosphino)methane)-diplatinum(0)

ChemInform, Jan 27, 1987

The synthesis of the title compound (II) occurs either by reduction of the dichloro‐Pt(II) monome... more

Fluxonial cryptands containing metallocene units

Journal of Organometallic Chemistry, Jun 1, 1986

... D. BEER*, CLARE DUDMAN, IAN P. DANKS, C. DENNIS HALL* Department of Chemistry, Kings College,... more

ChemInform Abstract: CARBONIUM IONS (246 LITERATURANGABEN)

Chemischer Informationsdienst, Jan 20, 1981

ChemInform Abstract: HOMOALLYLIC COUPLING IN 1,4-DIHYDRONAPHTHALENES. 3. CRYSTAL STRUCTURE OF 1,4-DIHYDRONAPHTHOIC ACID

Chemischer Informationsdienst, Aug 17, 1982

Die Kristallstruktur der Dihydro‐naphthalin‐1‐carbon‐ Säure (I) wird röntgenographisch im Verglei... more

ChemInform Abstract: Carbocntions (178 Literaturangaben)

Chemischer Informationsdienst, Sep 14, 1982

Acetolysis of 2-(2,3-dihydro-1H-cyclopenta[l]phenanthren-2-yl)ethyl derivatives: participation by the 9,10-bond of phenanthrene to give an analogue of a classical norbornyl cation

Journal of the Chemical Society, 1972

Kinetic and product studies of the title reaction indicate participation by the 9,10-bond of the ... more Kinetic and product studies of the title reaction indicate participation by the 9,10-bond of the phenanthrene ring. Preparative acetolysis of the bromide (5d) catalysed by silver acetate, gives 3,4-dihydro-2H-2,4a-methanotriphenylene (8) as a major product. This dissolves in fluorosulphonic acid to give a red solution, the 1H n.m.r. and electronic absorption spectra of which are consistent with the presence of the classical norbornyl cation (2A). Nucleophilic capture of the cation by acetic acid occurs predominantly at the bridge carbon atom, and is accompanied by ring opening to regenerate the cyclopentaphenanthrenylethyl skeleton.

Synthesis and Characterization of Methacrylate-Based Copolymers for Integrated Optical Applications

Chemistry of Materials, Nov 12, 2002

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Development of a novel bio-compatible polymer film for use as a Bruch’s membrane substitute

Investigative Ophthalmology & Visual Science, Apr 30, 2014

Purpose: To develop and optimise a co-polymer blend of poly(ethylene glycol methacrylate) (PEGM) ... more Purpose: To develop and optimise a co-polymer blend of poly(ethylene glycol methacrylate) (PEGM) and poly(methyl methacrylate) (PMMA) to act as a synthetic Bruch’s membrane (BrM) scaffold for primary murine retinal pigment epithelium (RPE) monolayers, as a potential treatment for dry age-related macular degeneration (AMD). This bio-compatible polymer film is designed to mimic BrM and to allow RPE cells to attach to the surface and proliferate, whilst retaining the necessary properties of human BrM, including porosity, thickness, biocompatibility and adhesion for the anchorage-dependant RPE cells. Methods: PEGM and PMMA are biocompatible polymers which are already in use for clinical applications. This co-polymer blend is functionalised at the PEGM site with N,N’-Disuccinimidyl carbonate and a RGDS peptide to facilitate RPE attachment. Electrospinning is used to produce polymer fibre sheets. By altering the parameters of the electrospinning apparatus (voltage, distance from needle to collector, flow rate) we can control the polymer fibre production. Results: By using the electrospinning technique, the co-polymer mat provides the necessary porosity, and by altering the parameters of the electrospinning, the thickness has been optimised to match human BrM (confirmed via an optical profiler, which found that the co-polymer had a thickness of approximately 12µm). The fidelity and effectiveness of the PMMA:PEGM co-polymer have been tested using long-term cultures of primary murine RPE monolayers. Our experiments also characterised RPE-barrier properties to establish the suitability of this novel synthetic scaffold for future transplantation studies Conclusions: This work demonstrates synthesis of a PMMA:PEGM co-polymer film, through the use of electrospinning, which mimics the properties of the BrM (porosity, thickness, biocompatibility and adhesion). This suggests that the electrospun membrane is a viable scaffold to facilitate delivery of RPE cells to the sub-retinal space. This is an exciting prospect and future work will investigate sub-retinal delivery of the co-polymer, via use of an in house designed and manufactured injector

Homoallylic coupling in 1,4-dihydronalenes

Journal of The Chemical Society-perkin Transactions 1, 1976

Bis(2,4,6trimethybenzyl)pyridine-2,6-dicarboxylate

Carbocations

John Wiley & Sons, Ltd eBooks, Feb 9, 2007

ChemInform Abstract: MULTINUCLEAR NMR INVESTIGATIONS OF BIS-μ-(BIS(DIPHENYLPHOSPHINO)METHANE)BIS(TRICHLOROSTANNIO)DIPLATINUM(PTPT) AND BIS-μ-(BIS(DIPHENYLPHOSPHINO)METHANE)CHLORO(TRICHLOROSTANNIO)DIPLATINUM(PTPT# ); OBSERVATION OF THE LARGEST RECORDED 3J

Chemischer Informationsdienst, Sep 21, 1982

Ausgehend von dem Dichlorokomplex (II) wurden durch Umsetzung mit SnCl2 abhängig vom Molverhältni... more

Carbonium Ions

John Wiley & Sons, Ltd eBooks, Feb 9, 2007

Influence of cation binding on the structure of adsorbed layers of crown ethers and amino acid derivatives at the air water interface

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Papers by Martin Grossel