Aliri Bioanalysis

👉Poster Download: https://conta.cc/3Xf9Vos In this scientific poster, our team aims to optimize and validate a qPCR workflow for the reproducible and sensitive quantification of immune checkpoint transcripts (PD-1,PD-L1, CTLA-4) in FFPE lung cancer tissues. By refining tissue preparation, RNA input, and assay conditions, we establish a robust method for detecting gene expression across a broad dynamic range, enabling reliable assessment of immunotherapy response and supporting biomarker-driven patient stratification. 👉Click here to download: https://conta.cc/3Xf9Vos

As therapies become increasingly complex and patient populations more biologically segmented, a critical gap stands between drug developers and tissue-level biological understanding of their molecule. Partner with Aliri for data that reveals local mechanisms, cellular interactions, and tissue remodeling for stronger regulatory submissions and smarter development decisions: https://lnkd.in/efEMMxeq

"Design an experiment to prove yourself right, and then design another 3 to prove yourself wrong." How are you safeguarding your method development process?

Are these common oligo bioanalysis mistakes compromising your data? Small oversights can have a major impact on LC-MS assay performance. Partner with Aliri for scientific control that achieves high-quality, regulatory-ready data every time. Learn more about our oligonucleotide bioanalysis services: https://lnkd.in/eDrbuFCr

👉 Scientific Poster Download: https://lnkd.in/enwFtTEu Learn how we improved bile acid analysis and reduced common testing challenges without adding extra cleanup steps.

Have you heard of the mechanistic evidence gap? More biomarker data doesn't necessarily lead to better decisions. By combining advanced tissue analytics with AI-driven insights, we're helping drug developers move beyond association and toward a deeper understanding of drug action, response, and resistance. Learn more: https://aliribio.com/

Aliri’s Clinical Analysis and Precision Execution (APEX) Process is built to run large clinical trials without the loss of scientific control, ensuring data remains robust, interpretable, and decision-ready as studies grow. Hundreds of sponsors have trusted us to run over 2 million clinical phase study samples. Learn how we can help you scale your development program with scientific control: https://lnkd.in/etb7qjPY

FDA guidance and recent regulatory discussions increasingly reference mechanistic, pharmacodynamic, and target engagement evidence as important components of confirmatory evidence frameworks. Here's how spatial biology can strengthen your regulatory package:

We're thrilled to welcome Aliri Bioanalysis as a Founding Member of CRO Marketplace. The strategic combination of three renowned legacy laboratories, Pyxant Labs, Tandem Labs, and ImaBiotech, Aliri Bioanalysis brings together 30 years of industry-leading expertise in regulatory-ready bioanalytical and predictive spatial biology services. With sites in Colorado Springs, Colorado, Salt Lake City, Utah, and Lille, France, Aliri supports drug development from discovery through late clinical-phase analysis. Bioanalytical capabilities span small and large molecules, RNAi therapeutics, LNPs, ADCs, peptide and protein therapeutics, and biomarkers across platforms including LC-MS/MS, LC-HR/MS, qPCR, and CyTOF. Spatial services include ready-to-use biomarker panels for clinical spatial tissue analysis, AI-powered spatial multi-omics, in situ PK-PD, histopathology and biodistribution. Their Lille, France laboratory, an ISO-certified center of excellence for spatial bioanalysis, holds six patents, and has published dozens of scientific papers in the field. Aliri also brings a proprietary AI workflow to help sponsors gain high-resolution insights into their molecule's mechanism of action at the single-cell level, enabling more strategic decision making throughout development. Learn more about Aliri Bioanalysis at 🔗 www.aliribio.com Connect. Promote. Collaborate. Be visible. 🌐 www.cromarketplace.com #CROMarketplace #AliriBioanalysis #Bioanalysis #SpatialBiology #LCMS #DrugDevelopment #Pharma #Biotech #LifeSciences #ADC #LNP

Poster Download > https://conta.cc/4vJeTta ADCs achieve therapeutic activity only when payload delivery, target accessibility, and microenvironmental readiness align within tumor tissue. Conventional biomarkers capture isolated components of this biology but fail to resolve the spatial coordination that ultimately governs pharmacodynamic activity. To address this gap, we developed a translational spatial PK/PD framework integrating MSI, spatial proteomics/transcriptomics, and multiplex tissue imaging to spatially interpret coordinated ADC activity within solid tumors. Download the poster, recently presented at EACR 2026 in Budapest, Hungary to learn more.