Bondus

𝐎𝐄𝐌 𝐢𝐧𝐭𝐞𝐠𝐫𝐚𝐭𝐢𝐨𝐧 𝐢𝐧 𝐦𝐢𝐜𝐫𝐨𝐟𝐥𝐮𝐢𝐝𝐢𝐜𝐬 Inside a diagnostic platform or analytical instrument, elaborate fluid or gas networks can be replaced by a manifold. This miniaturizes the network while maintaining precise control of fluid or gas flow. Bondus offers the manufacturing of manifolds in industrial-grade polymers such as PC, COC, COP, PMMA, PS, and PETG. Multi-layer designs are precision-machined and bonded to create complex and three-dimensional flow paths. Beyond just bonding the manifold layers, Bondus provides complete assembly, including microvalves, sensors, electronics, and tube connectors. Functional testing is then performed to confirm functionality. Read more about our microfluidic OEM integration capabilities:  https://lnkd.in/e7aJQUEq #OEM #Microfluidics #Diagnostics #LabOnChip #ValveIntegration #FluidHandling 

𝗦𝗰𝗮𝗹𝗮𝗯𝗹𝗲 𝗺𝗶𝗰𝗿𝗼𝗳𝗹𝘂𝗶𝗱𝗶𝗰𝘀: 𝗰𝗼𝗻𝘀𝗶𝘀𝘁𝗲𝗻𝗰𝘆 𝗶𝗻 𝗲𝘃𝗲𝗿𝘆 𝗯𝗮𝘁𝗰𝗵 A working prototype shows that the recipe works. Scalable production means making sure every batch turns out the same. For microfluidic devices, this goes beyond the first successful sample. It requires control over the quality of raw materials, dimensional tolerances, bonding methods, and other assembly processes. Bondus supports customers through the transition from prototyping to volume manufacturing. We provide advice on Design for Manufacturing and develop dedicated tooling and automation to increase production capacity and reduce production costs. Learn more about our microfluidic manufacturing capabilities:  https://lnkd.in/ey_37RpM #Microfluidics #MicrofluidicManufacturing #Scaling #ProductDevelopment #Diagnostics #MedTech 

𝗧𝗵𝗲 𝗿𝗶𝗴𝗵𝘁 𝗯𝗼𝗻𝗱𝗶𝗻𝗴 𝗺𝗲𝘁𝗵𝗼𝗱 𝗳𝗼𝗿 𝘀𝗰𝗮𝗹𝗮𝗯𝗹𝗲 𝗺𝗶𝗰𝗿𝗼𝗳𝗹𝘂𝗶𝗱𝗶𝗰𝘀 The choice of a bonding method impacts far more than just the seal between layers. It also influences material selection, microchannel integrity, tolerances, pressure resistance and, ultimately, the manufacturability of the microfluidic device. At Bondus, we select the right bonding approach early in the development process. Every material, fluidic design and application requires careful consideration. What works well for a prototype should also support the next step towards reproducible manufacturing. Bondus develops and manufactures bonded microfluidic devices in polymers, glass and hybrid materials, with a strong focus on reliable sealing while preserving critical microfluidic features such as channels, valves, filters, mixers and optical windows. Learn more about our microfluidic bonding capabilities:  https://lnkd.in/ej5Qi7x3 #Microfluidics #MicrofluidicBonding #LabOnChip #Diagnostics #MicroManufacturing

𝐂𝐮𝐬𝐭𝐨𝐦 𝐰𝐞𝐥𝐥 𝐩𝐥𝐚𝐭𝐞𝐬 𝐟𝐨𝐫 𝐚𝐝𝐯𝐚𝐧𝐜𝐞𝐝 𝐜𝐞𝐥𝐥 𝐜𝐮𝐥𝐭𝐮𝐫𝐢𝐧𝐠 Are you working on organoid cultures, spheroid assays, organ-on-chip research, or drug testing? Then a controlled culture environment is essential at every step of the workflow. Bondus manufactures well plates with integrated micro-cavities to create micro-environments in standard 96- and 384-well SBS formats. The video shows such a custom well plate, with 19 micro-cavities of 400µm densely packed into a single well. This allows us to create custom solutions in a standard plate format for high throughput applications in stem cell screening, organoid culturing, personalized medicine, and regenerative medicine. Explore our manufacturing approach of these microplates:  https://lnkd.in/eS86mbSk #Organoids #Spheroids #OrganOnChip #Microfluidics #DrugTesting #Microplates 

𝐏𝐨𝐥𝐲𝐦𝐞𝐫 𝐭𝐨 𝐠𝐥𝐚𝐬𝐬 𝐛𝐨𝐧𝐝𝐢𝐧𝐠 For applications where optical transparency is important, we have the ability to integrate glass layers in microfluidic products. This lab-on-a-chip is a perfect example: a 140 µm thick glass cover is bonded with a COC or PMMA substrate. Bonding is performed using an adhesive specifically designed to remain optically transparent after curing. 𝐖𝐡𝐲 𝐩𝐨𝐥𝐲𝐦𝐞𝐫 𝐚𝐧𝐝 𝐠𝐥𝐚𝐬𝐬 𝐢𝐧 𝐨𝐧𝐞 𝐝𝐞𝐯𝐢𝐜𝐞? • Hybrid bonding of glass to polymers creates optical windows for microscopy or imaging applications;  • While glass is chemically inert, flat and has excellent optical characteristics, polymers can be more easily micro-structured and (bio)functionalised;  • Glass-glass bonding requires very high temperatures. Bondus can bond glass to polymers at room temperature, keeping production simple and cost-effective. Interested? Reach out to us at info@bondus.nl or connect with us on LinkedIn. #Microfluidics #HybridBonding #GlassToPolymer #PrecisionBonding #Optical

𝐌𝐚𝐣𝐨𝐫 𝐦𝐢𝐥𝐞𝐬𝐭𝐨𝐧𝐞 𝐚𝐜𝐡𝐢𝐞𝐯𝐞𝐝: 𝐁𝐨𝐧𝐝𝐮𝐬 𝐢𝐬 𝐈𝐒𝐎 13485 𝐜𝐞𝐫𝐭𝐢𝐟𝐢𝐞𝐝! Over the past six months, our team has built and implemented a fully electronic Quality Management System. Today, we are proud to announce that Bondus has officially received its ISO 13485 certification from BSI . This certificate demonstrates our commitment to quality, regulatory compliance, and continuous improvement in manufacturing medical devices and in vitro diagnostic devices. With our QMS now fully operational, we have set up a solid foundation for scaling production while consistently delivering high-quality products. Download the certificate on our website: https://lnkd.in/eaJXeAdM #ISO13485 #QualityManagement #MedicalDevices #Compliance #InVitroDiagnostics

𝐑𝐨𝐦𝐞 𝐰𝐚𝐬𝐧'𝐭 𝐛𝐮𝐢𝐥𝐭 𝐢𝐧 𝐚 𝐝𝐚𝐲. 𝐀 𝐜𝐥𝐞𝐚𝐧𝐫𝐨𝐨𝐦 𝐜𝐞𝐫𝐭𝐚𝐢𝐧𝐥𝐲 𝐢𝐬𝐧'𝐭 𝐞𝐢𝐭𝐡𝐞𝐫! 𝐎𝐧𝐜𝐞 𝐜𝐨𝐦𝐩𝐥𝐞𝐭𝐞𝐝, 𝐨𝐮𝐫 𝐧𝐞𝐰 𝐜𝐥𝐞𝐚𝐧𝐫𝐨𝐨𝐦 𝐰𝐢𝐥𝐥 𝐢𝐧𝐜𝐫𝐞𝐚𝐬𝐞 𝐁𝐨𝐧𝐝𝐮𝐬' 𝐩𝐫𝐨𝐝𝐮𝐜𝐭𝐢𝐨𝐧 𝐚𝐫𝐞𝐚 𝐟𝐢𝐯𝐞𝐟𝐨𝐥𝐝. The construction of our new cleanroom has taken a huge step already. In only two weeks an empty slab of concrete has been filled with a big empty shell that will be our new production space. But there remains much work to be done in both construction and validation before this new location can be used. 𝐖𝐡𝐚𝐭 𝐝𝐨𝐞𝐬 𝐚 𝐜𝐥𝐞𝐚𝐧𝐫𝐨𝐨𝐦 𝐝𝐨? Cleanrooms provide the environmental conditions that are necessary to make production of microdevices reliable. • ISO 6/7 particle cleanliness to prevent contamination of the microfluidic devices with dust or other contamination. • Temperature and humidity control ensure that micro-dispensing processes for coatings and biomarkers are repeatable and consistent.

𝗘𝘅𝗽𝗮𝗻𝗱𝗶𝗻𝗴 𝗼𝘂𝗿 𝗺𝗮𝘁𝗲𝗿𝗶𝗮𝗹 𝗽𝗼𝗿𝘁𝗳𝗼𝗹𝗶𝗼: 𝗶𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝘁𝗶𝗻𝗴 𝗣𝗘𝗜  One of the latest additions to our portfolio is bonded manifolds and microfluidic products in PEI, also known as Ultem. This material, with its typical amber colour, is commonly used for manifolds, but is still less often seen in microfluidics. PEI is a hard and strong engineering plastic, making it an interesting choice for robust microfluidic components and manifold products. 𝗪𝗵𝘆 𝗣𝗘𝗜? While COC and COP are also known as suitable materials for applications requiring chemical resistance or high temperature resistance, there is a clear distinction in solvent resistance between these materials. -𝗖𝗢𝗖/𝗖𝗢𝗣 performs well with polar solvents such as alcohols and ketones, but is less suitable for non-polar solvents such as n-heptane or aromatic solvents. -𝗣𝗘𝗜 𝗽𝗲𝗿𝗳𝗼𝗿𝗺𝘀 well with alcohols, non-polar solvents and even most aromatic solvents. However, it is not suitable for applications where ketones or esters are used. Want to learn more about our capabilities for microfluidic devices and manifold products? View our brochure on our website: https://www.bondus.nl/ #microfluidics #PEI #Ultem #bondedmanifolds #microfluidicdevices #manifolds #materialselection

𝐌𝐨𝐬𝐭 𝐩𝐞𝐨𝐩𝐥𝐞 𝐨𝐧𝐥𝐲 𝐬𝐞𝐞 𝐭𝐡𝐞 𝐟𝐢𝐧𝐢𝐬𝐡𝐞𝐝 𝐦𝐢𝐜𝐫𝐨𝐟𝐥𝐮𝐢𝐝𝐢𝐜 𝐝𝐞𝐯𝐢𝐜𝐞. What they don't see is the inspection process behind it. In microfluidics, small deviations can have a significant impact on performance. Channel quality, layer alignment, bonding integrity and dimensional accuracy all play a role in how a device ultimately functions. That is why inspection is an important part of our manufacturing process. Depending on the application, devices are carefully checked using microscopes, measurement equipment and visual inspections to verify critical features before they move to the next stage. Because in microfluidics, quality is often determined by details that are barely visible to the naked eye. Discover how Bondus supports projects from concept to production: https://www.bondus.nl #Microfluidics #QualityControl #Manufacturing #LabOnChip #Bondus

CNC micro-machining is not only ideal for bonded manifolds. It also plays an important role in the rapid prototyping of microfluidic products. At Bondus, we use this technology in-house to keep throughput times short and maintain full control over quality. With micro-cutters and drills, we can create complex fluidic networks with high precision. By adding an additional polishing step, we can achieve optical-quality channels, even for channels as small as 0.3 mm. A key advantage over 3D printing is material choice. CNC micro-machining allows us to work with materials that can also be transferred to injection molding, such as COC, PMMA, PC and PEI. This makes it easier to move from prototype to production. Curious how CNC micro-machining could support your microfluidic prototype or product development? Visit: https://www.bondus.nl #Bondus #Microfluidics #RapidPrototyping #CNCMicromachining #BondedManifolds