SynCardia Systems, LLC

Behind every beat is the heart of our mission. In this video, Melissa Morales shares what it means to support the teams behind SynCardia’s work every day. As Executive Assistant and Office Manager, Melissa helps keep projects moving, teams connected, and our mission at the center of it all. Every role at SynCardia contributes to supporting patients living with advanced heart failure.

We're proud to share coverage from MassDevice highlighting the completion of a milestone preclinical study series for our Emperor Total Artificial Heart platform.   In these animal model studies, the device demonstrated early circulatory support performance, generating data that will inform continued development. We are advancing the Emperor TAH with the goal of expanding treatment options for patients with advanced heart failure.   The Emperor Total Artificial Heart is an investigational device and has not been cleared or approved by the FDA for commercial use. Read more in MassDevice's coverage below: https://lnkd.in/gC62SfVa #SynCardia #ArtificialHeart #HeartFailure #MedTech

The SynCardia Total Artificial Heart (STAH) was designed to provide circulatory support for patients with severe biventricular heart failure while they wait for a heart transplant. This video takes a closer look at the technology, innovation, and purpose behind the STAH system. Learn more at SynCardia.com.

Not all heart failure is the same. The most critical patients, those with end stage biventricular failure, require support beyond what partial devices can provide. For these patients, complete circulatory replacement becomes the path forward. Centers that become TAH capable gain the ability to treat the full spectrum of heart failure, including cases that would otherwise have no options. That capability strengthens the entire program, expanding surgical breadth, deepening collaboration, and elevating the standard of care across the team. The SynCardia Total Artificial Heart is the only FDA and Health Canada approved total artificial heart available in the United States and Canada. Centers that adopt it often describe the impact as program defining, shaping not only patient care but the clinical identity of the institution. Being TAH capable signals a commitment that stands apart. A willingness to treat the cases others cannot. If your program is exploring Total Artificial Heart capability, we welcome the conversation. Learn more at: www.syncardia.com

Reaching transplant is only part of the journey. Getting there in the best possible condition is what matters most. The SynCardia Total Artificial Heart has a proven track record as a bridge to transplant, with 52 percent of patients reaching transplant within 12 months based on U.S. registry data. More importantly, this reflects sustained physiological stability, patients who are not just surviving while they wait, but remaining stable, eligible, and ready for what comes next. The best bridge to transplant maintains the body’s readiness for the next stage. That is what SynCardia Systems is built to do. Data derived from the INTERMACS registry were presented in the abstract “Beyond Survival: Defining Success After Total Artificial Heart Implantation” at Technology and Heart Failure Therapeutics 2026.

Meet Marcela: Four days after giving birth to her son Santiago in 2010, Marcela could not catch her breath. Born with a congenital heart condition, her heart had been pushed beyond what it could bear. She was 20 years old, Santiago was four months old, and she was facing end-stage heart failure. Marcela received the SynCardia Total Artificial Heart at Banner Health University Medical Center in Tucson. Once she stabilized, she was transitioned to the Freedom portable driver and discharged home in January 2011, becoming the first woman in the United States to leave the hospital powered by the Freedom driver. She came home just in time for her 21st birthday. For 245 days, Marcela did not slow down. She took Santiago to the zoo, walked trails, rode her bike, and showed up for her son every single day. Then on May 27, 2011, the call came. Marcela received her donor heart. "You never know when it is going to be the last time. The artificial heart was my second chance." Today she hikes with Santiago, the same boy she was not sure she would get to watch grow up, and she does not take a single moment for granted. "After receiving my heart transplant, my life blossomed. I witnessed my son grow, achieved personal goals, established a home, traveled, and celebrated holidays with family. I emphasize the importance of seizing opportunities today, as tomorrow is uncertain." Marcela, thank you for sharing your story. You are the reason we do this work.

Connection is just as powerful as innovation. In this video, Ella Marshall shares what inspires her in her work at SynCardia, a standout moment from her time here, and what keeps her feeling deeply connected to the mission behind everything we do. What helps you stay connected to your work?

Behind every breakthrough in medicine is a hospital where it becomes reality. This National Hospital Week, SynCardia recognizes the cardiac centers, surgical teams, and hospital staff who make life saving care possible for patients with advanced heart failure. The SynCardia Total Artificial Heart has been implanted more than 2,100 times across 27 countries. That progress is made possible by hospitals that invest in new technology, train their teams, and commit to supporting their most critical patients while they wait for a donor heart. From the operating room, to the ICU, to discharge, every department plays a role in the patient journey. We are honored to work alongside institutions that share a commitment to advancing care and improving lives. To every hospital team doing this work every day, this week is for you.

To every nurse who has held a patient’s hand, stayed late to check on a chart, and shown up with both skill and heart, thank you. This National Nurses Week, SynCardia Systems recognizes the nurses who support our patients every day. Caring for a patient with a Total Artificial Heart requires precision, dedication, and a deep commitment to the person behind the diagnosis. Nurses bring all of that and more. They are central to the care teams at the hospitals and cardiac centers we partner with across the country, and their work is part of every patient success we celebrate. We are grateful for you. We see the work you do and we do not take it for granted.

A great day at University of Arizona College of Engineering Design Day! We had the opportunity to see our sponsored Capstone team present their project: “Durability Test Apparatus for SynCardia’s Emperor Total Artificial Heart (ETAH).” Their work advances how we test the reliability of total artificial hearts by creating a more compact and rigorous mock tank system. “I am proud of what our Capstone team has accomplished and grateful for their support,” said their SynCardia Systems, LLC mentor, Duffy Elmer. Congratulations to the team on an impressive achievement—we’re excited to see what’s next!