Reconstructing Thin Walls in Spray-Dried Dispersions for Improved Tablet Performance

Here's a scientific solution we're proud of.   In spray-dried dispersions, particle wall thickness affects how a tablet compacts, holds together, and dissolves. But these walls are so thin they sit at the resolution limit of micro-CT. Standard image processing techniques fail to properly segment these walls due to resolution and contrast limitations, missing critical microstructural information that affects product performance.   digiM patented a method that reconstructs those thin walls from the image, reading their shape and curvature to recover a real, measurable number. Published work ties the reconstructed wall thickness to tablet strength, porosity, and dissolution, further proving its effectiveness.   Good science solves real problems. #microstructure #digiM #pharma #dissolution #spraydrieddispersion

  • No alternative text description for this image

To view or add a comment, sign in

Explore content categories