Here's a scientific solution we're proud of. In spray-dried dispersions, particle wall thickness affects how a tablet compacts, holds together, and dissolves. But these walls are so thin they sit at the resolution limit of micro-CT. Standard image processing techniques fail to properly segment these walls due to resolution and contrast limitations, missing critical microstructural information that affects product performance. digiM patented a method that reconstructs those thin walls from the image, reading their shape and curvature to recover a real, measurable number. Published work ties the reconstructed wall thickness to tablet strength, porosity, and dissolution, further proving its effectiveness. Good science solves real problems. #microstructure #digiM #pharma #dissolution #spraydrieddispersion
Reconstructing Thin Walls in Spray-Dried Dispersions for Improved Tablet Performance
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From vascular grafts to tissue reconstruction, ePTFE's unique microporous structure continues revolutionizing medical device design and patient outcomes worldwide. Taanisha Mukhopadhyay, a chemical and metallurgy engineer with Balmer Lawrie & Co. Ltd., tells PlasticsToday the success of ePTFE in medical applications stems from its distinctive microstructure. Check out our coverage here: https://lnkd.in/e8G4EyEn
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The science behind an implant surface doesn't stop after manufacturing. Learn how the calcium phosphate layer on nanoVIS Ti™ helps protect the engineered surface during storage before implantation. Watch the video, then explore the science behind our technology. 🔗 https://lnkd.in/eeFyuGbm #Nanotechnology #SurfaceTechnology
Calcium Phosphate Surface: Protects Nanotubes, Dissolves Away
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🔬 Cucurbit[10]uril ✨ Explore how cucurbit[10]uril’s expansive cavity, iodine‑sequestering barrel, and fluorescence‑boosting ability redefine host‑guest chemistry for advanced materials. These three properties illustrate the molecule’s role in designing smarter antimicrobial surfaces, ultrasensitive pollutant sensors, and new supramolecular architectures since its 2014 discovery. ✓ 🧪 1. Discovered 2014, cucurbit[10]uril has ten glycoluril units, forming the largest cucurbituril cavity, accommodating guests up to ~14 Å. ✓ 🛡️ 2. Its barrel shape tightly binds molecular iodine, stabilizing it for slow‑release antimicrobial coatings on medical devices. ✓ 🌟 3. When complexed with cationic dyes, cucurbit[10]uril dramatically enhances fluorescence, enabling ultra‑sensitive detection of trace pollutants. 🟢 What applications do you envision for cucurbit[10]uril’s unique binding and fluorescence features? #Supramolecular #Cucurbituril #HostGuest #Antimicrobial #Fluorescence
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🔬 Cucurbit[10]uril ✨ Explore how cucurbit[10]uril’s expansive cavity, iodine‑sequestering barrel, and fluorescence‑boosting ability redefine host‑guest chemistry for advanced materials. These three properties illustrate the molecule’s role in designing smarter antimicrobial surfaces, ultrasensitive pollutant sensors, and new supramolecular architectures since its 2014 discovery. ✓ 🧪 1. Discovered 2014, cucurbit[10]uril has ten glycoluril units, forming the largest cucurbituril cavity, accommodating guests up to ~14 Å. ✓ 🛡️ 2. Its barrel shape tightly binds molecular iodine, stabilizing it for slow‑release antimicrobial coatings on medical devices. ✓ 🌟 3. When complexed with cationic dyes, cucurbit[10]uril dramatically enhances fluorescence, enabling ultra‑sensitive detection of trace pollutants. 🟢 What applications do you envision for cucurbit[10]uril’s unique binding and fluorescence features? #Supramolecular #Cucurbituril #HostGuest #Antimicrobial #Fluorescence
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🔬 Cucurbit[10]uril ✨ Explore how cucurbit[10]uril’s expansive cavity, iodine‑sequestering barrel, and fluorescence‑boosting ability redefine host‑guest chemistry for advanced materials. These three properties illustrate the molecule’s role in designing smarter antimicrobial surfaces, ultrasensitive pollutant sensors, and new supramolecular architectures since its 2014 discovery. ✓ 🧪 1. Discovered 2014, cucurbit[10]uril has ten glycoluril units, forming the largest cucurbituril cavity, accommodating guests up to ~14 Å. ✓ 🛡️ 2. Its barrel shape tightly binds molecular iodine, stabilizing it for slow‑release antimicrobial coatings on medical devices. ✓ 🌟 3. When complexed with cationic dyes, cucurbit[10]uril dramatically enhances fluorescence, enabling ultra‑sensitive detection of trace pollutants. 🟢 What applications do you envision for cucurbit[10]uril’s unique binding and fluorescence features? #Supramolecular #Cucurbituril #HostGuest #Antimicrobial #Fluorescence
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Resharing this post. A favorite visual from the series, one binder design, many encoded colors, and why holding the chemistry constant makes multiplexing far less painful. #InsideTheFluorAbodyEngine
One binder design, many fluorophores. Because the color is encoded, you can swap the fluorescent protein without changing the binding chemistry, so you can multiplex with confidence and minimal cross-talk. More targets, same predictable behavior. #Multiplexing #Imaging #Microscopy #InsideTheFluorAbodyEngine
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As medical devices become more sophisticated, giving engineers greater design flexibility is increasingly important. Meta-Poly® is an exciting example of how conductive functionality can be integrated into polymer components without compromising their performance. Looking forward to seeing how this technology continues to expand what's possible in minimally invasive device design.
That's why ProPlate® developed Meta-Poly®, a proprietary metallization technology that applies metal directly to polymer substrates while preserving their flexibility and performance. ☑️ By eliminating the need for chemical etching or conductive paints, Meta-Poly® enables engineers to integrate electrical conductivity into complex polymer components without compromising design intent. Whether you're developing #catheter-based systems, #electrophysiology devices, or other minimally invasive technologies, Meta-Poly® helps expand what's possible in medical device design. Discover how ProPlate® is advancing polymer metallization with Meta-Poly®. Learn more: www.proplate.com 💡 #MetaPoly #ProPlate #medicaldevices #biomedicalengineering #electroplating #medicaiInnovation #surfaceengineering #selectiveplating #medicalgoldplating #platinumplating
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Adding conductivity to a polymer component usually means adding process. Chemical etching, conductive paints, secondary bonding steps. Each one adds a variable and a place where the part can drift. ProPlate®'s Meta-Poly process applies metal directly to polymer substrates without those intermediate steps, and keeps the flexibility of the base material intact. Worth a look for EP electrodes and catheter subassemblies where conductivity and polymer performance both need to hold.
That's why ProPlate® developed Meta-Poly®, a proprietary metallization technology that applies metal directly to polymer substrates while preserving their flexibility and performance. ☑️ By eliminating the need for chemical etching or conductive paints, Meta-Poly® enables engineers to integrate electrical conductivity into complex polymer components without compromising design intent. Whether you're developing #catheter-based systems, #electrophysiology devices, or other minimally invasive technologies, Meta-Poly® helps expand what's possible in medical device design. Discover how ProPlate® is advancing polymer metallization with Meta-Poly®. Learn more: www.proplate.com 💡 #MetaPoly #ProPlate #medicaldevices #biomedicalengineering #electroplating #medicaiInnovation #surfaceengineering #selectiveplating #medicalgoldplating #platinumplating
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Excited to share how Meta-Poly® is helping medical device engineers rethink what's possible with polymer components. This technology enables selective metallization while maintaining the mechanical properties critical to next-generation minimally invasive devices.
That's why ProPlate® developed Meta-Poly®, a proprietary metallization technology that applies metal directly to polymer substrates while preserving their flexibility and performance. ☑️ By eliminating the need for chemical etching or conductive paints, Meta-Poly® enables engineers to integrate electrical conductivity into complex polymer components without compromising design intent. Whether you're developing #catheter-based systems, #electrophysiology devices, or other minimally invasive technologies, Meta-Poly® helps expand what's possible in medical device design. Discover how ProPlate® is advancing polymer metallization with Meta-Poly®. Learn more: www.proplate.com 💡 #MetaPoly #ProPlate #medicaldevices #biomedicalengineering #electroplating #medicaiInnovation #surfaceengineering #selectiveplating #medicalgoldplating #platinumplating
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That's why ProPlate® developed Meta-Poly®, a proprietary metallization technology that applies metal directly to polymer substrates while preserving their flexibility and performance. ☑️ By eliminating the need for chemical etching or conductive paints, Meta-Poly® enables engineers to integrate electrical conductivity into complex polymer components without compromising design intent. Whether you're developing #catheter-based systems, #electrophysiology devices, or other minimally invasive technologies, Meta-Poly® helps expand what's possible in medical device design. Discover how ProPlate® is advancing polymer metallization with Meta-Poly®. Learn more: www.proplate.com 💡 #MetaPoly #ProPlate #medicaldevices #biomedicalengineering #electroplating #medicaiInnovation #surfaceengineering #selectiveplating #medicalgoldplating #platinumplating
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