JAX Tech Talk

Have you signed up? The JAX Pulse Newsletter is your easiest way to stay informed about the latest launches of innovative mouse and cell models, or to view our calendar of webinars and events you can add to your calendar. Delivered monthly, and read by thousands of scientists worldwide - join in! https://bit.ly/4htbLNH

⏰ The JAX Cancer Short Course is less than a month away! Have you registered yet? The Jackson Laboratory's signature cancer training program will give you the opportunity to learn from renowned scientists and gain practical insights you can apply to your own research. 💻 Register to participate virtually from anywhere with access to recorded content: https://lnkd.in/e7K6utiZ

Why is C57BL/6J so Important in Biomedical Research? It’s critical to understand the mouse models you rely on as part of your research. Join Corigan Smothers, JAX Technical Information Scientific Consultant, on July 16th for our live, virtual webinar, where you’ll learn the defining features of the C57BL/6J strain and gain practical insights on features of this model that are widely used in research, including: • Strain Origin: Understand the history and development of C57BL/6J • Genetic Stability: Learn how consistency is maintained in modern colonies • Research Applications: Explore its strengths from model generation to key research areas • Study Considerations: Examine known irregularities and their impact on study design and colony management Register in comments. Live, free-to-attend virtual event – happening July 16, 2026 at 1 p.m (EST)

Natural Killer (NK) cells occupy an intriguing niche between adaptive and innate immunity, and their mechanisms of action have become the focus of promising candidates for immunotherapies, with several clinical trials underway. While we have yet to FDA-approved drugs become available, the use of innovative humanized mouse models is bringing this goal closer to reality. In our new article, we explore the research, the complexity of NK cell biology, and the application of CD34+ (HSC) and PBMC-engrafted models to generate actionable data toward this end. See the data from Dr. Martin Felices for analysis of PBMC-engrafted models where B cells are targeted by a CD19-specific TriKE, as well as a CD19-expressing tumor. Their patient-specific data reveals insights in an autologous system where both tumor and PBMCs from the same patient may provide near-future potential for NK-directed therapy. Link in comments!

Antibody therapeutics are redefining precision medicine—moving beyond broad treatments to highly targeted, immune-driven approaches. But success starts with understanding both biology and platform strategy. Join our upcoming webinar: 🎥 ABCs of Antibody Discovery: Leveraging Biological Foundations and Modern Platforms You’ll learn: ➡️ Key mechanisms like ADCC, neutralization, and complement activation ➡️ The full antibody discovery workflow ➡️ How to evaluate platforms like phage display, hybridoma, and transgenic models The link to register is in the comments ⤵️

Searching for the right Alzheimer's disease model? Join the JAX Technical Information Scientists this week on June 25 at 1 p.m. ET to explore the JAX Alzheimer's (AD) models making an impact today, what's coming next through the MODEL-AD consortium (including late-onset AD models), and how to choose the right fit for your research. Register at the link in the comments to secure your spot. 🧠

Curious about human-induced pluripotent stem cells (iPSCs) and how they're reshaping human disease modeling? Join the JAX Technical Information Scientist team on June 16 at 1:00 p.m. ET to find out. We'll cover iPSC basics, real-world research applications, and the biological questions these models help answer, plus an introduction to the JAX iPSC catalog and best practices for getting started. Register at the link in comments to secure your spot.