Summer temperatures are rising — so we’re cooling down the barriers to organ-on-chip adoption. 🌡️❄️ With our DynamicOrgan® Starter Kit promotion, research teams can get started for under €500 and receive free 2-month access to our Online Academy. Because exploring human-based models should feel practical, not overwhelming. Terms & Conditions apply Learn more here: https://zurl.co/QmgBO
Dynamic42 GmbH
Biotechnologieforschung
Jena, Thüringen 4.094 Follower:innen
Develop human organ models with true physiological complexity
Info
We are specialized in the production and development of human, immunocompetent Organ-on-Chip technology for in vitro disease and infection modelling.
- Website
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http://www.dynamic42.com
Externer Link zu Dynamic42 GmbH
- Branche
- Biotechnologieforschung
- Größe
- 11–50 Beschäftigte
- Hauptsitz
- Jena, Thüringen
- Art
- Privatunternehmen
- Gegründet
- 2018
- Spezialgebiete
- Organ-on-Chip, Human Cell Biology, Infection, Infectious disease, Toxicity profiling, Immune Cell Interactions, Inflammatory Diseases, Antibody recycling und Uptake / Transport studies
Orte
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Primär
Wegbeschreibung
Winzerlaer Straße 2
Jena, Thüringen 07745, DE
Beschäftigte von Dynamic42 GmbH
Updates
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In part 5 of Minds Behind Organ-on-Chip season 2, we continue our video interview series spotlighting researchers who are advancing MPS and organ-on-chip technologies. At the EUROoCS Annual Meeting 2026, we had the pleasure of speaking with Christian Maass, lead of the MPSlabs business unit at ESQlabs. Chris shared insights into the work of MPSlabs and our collaboration on predicting placental transfer of drugs during pregnancy. Together, we combined in vitro data on drug metabolism and transport from a gut-liver-placenta model with MPSlabs’ expertise in digital twinning to help predict fetal drug exposure. By bringing together in silico predictions and in vitro data, this approach can reduce the use of animal models and support better decision-making before drugs enter clinical studies. Curious to see what else is happening in the organ-on-chip community? We’ll be sharing more stories in the coming weeks, so follow us for more videos. #organonchip #mps
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Organ-on-chip methods are opening up new possibilities for human-relevant biomedical research from disease modelling and infection research to preclinical drug development and personalized medicine. By combining human cells with dynamic microphysiological conditions such as perfusion, tissue-tissue interfaces and biomechanical stimulation, organ-on-chip models can help bridge the gap between conventional cell culture and animal models. But we’re curious: In which research area do you see the greatest potential for organ-on-chip methods? Vote in the poll and let us know your perspective in the comments. #OrganOnChip #MicrophysiologicalSystems #BiomedicalResearch #DrugDevelopment #DiseaseModeling #InVitroModels
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In part 4 of Minds Behind Organ-on-Chip season 2, we continue our video interview series spotlighting researchers advancing MPS and organ-on-chip technologies. At EUROoCS Annual Meeting 2026, we met Nanci Santos Ferreira, PostDoc at the Porto Lab at KU Leuven in Belgium. Nanci introduced us to her work on developing a human intestinal enteroid-derived gut-on-chip model to study the replication and dissemination of Hepatitis E Virus (HEV) along the gut-liver-axis. Curious to see more case studies of the organ-on-chip community? At EUROoCS, we met many more scientists developing organ models across a wide range of fields. We’ll be sharing their stories in the coming weeks, so follow us and don't miss any video. #organonchip #mps
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We are at the Jena School for Microbial Communication (JSMC) Retreat 2026 in Jena! Meet our colleague Franziska Hausig-Punke, PhD to learn how organ-on-chip technology can support microbiology and infection biology research with human-relevant in vitro models. We’re excited to see our technology being applied across different research projects, exchange ideas with the scientific community, connect with new faces and support young scientists in their early career stages. Thank you to the JSMC Excellence Graduate School for hosting us! 😊 #organonchip #microbiology #infection
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Too hot to overthink your next lab investment? We’ll keep it simple. ☀️ DynamicOrgan® Starter Kits are available this summer for under €500, including free 2-month access to our Online Academy. A low-risk first step for teams ready to explore organ-on-chip technology. Terms & Conditions apply Learn more here: https://zurl.co/rCDao
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In part 3 of Minds Behind Organ-on-Chip season 2, we continue our video interview series spotlighting researchers advancing MPS and organ-on-chip technologies. We visited Mark Gresnigt, Junior Research Group Leader of the Adaptive Pathogenicity Strategies group at the Leibniz Institute for Natural Product Research and Infection Biology in Germany. He spoke with us about his work on the host pathogen interactions during the infection with the yeast Candida albicans in gut- and vaginal mucosa-on-chip models. Over the coming weeks, we’ll share more interviews with researchers developing organ models across a range of fields and highlighting the exciting work behind them. Follow us and don’t miss a single video! #organonchip #mps
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Dynamic42 GmbH hat dies direkt geteilt
📊 The latest UK Understanding Animal Research statistics published yesterday are striking! Over the past 5 years, Imperial College London has reduced the number of animals used in research by 52%, while the average among the other major organizations remained broadly unchanged. 👇 🐁 Imperial now uses fewer than one-quarter of the animals used by any of the top users (Crick, Oxford, Cambridge), while 10 years ago Cambridge and Imperial used nearly the same number of animals (~115,000 per year). 🔬 This change is not because Imperial is doing less research. Just the opposite. 🧫 This is because of strategic investment in human-relevant research, many in the NIHR Imperial Biomedical Research Centre: a disease-agnostic, diverse tissue bank, advanced clinical data infrastructure, the UK’s largest organoid facility, and bioengineering platforms enabling miniaturized, animal-free and advanced in vitro models. 🌐 And this is working: during the same 5-year period, Imperial has become the top1 university in the UK (and Europe) in multiple ranking systems. 💡 The message is clear: it is possible to use fewer animals and deliver better, more human-relevant research. 🤝 These capabilities have been made possible thanks to funding from NIHR (National Institute for Health and Care Research), EPSRC, Medical Research Council, BBSRC and National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), alongside technologies from HUB Organoids, STEMCELL Technologies, Qkine, Emulate, Inc., MEPSGEN, MIMETAS, Dynamic42 GmbH, CN Bio and ProDigest and many others to investigate human diseases with human models. #HumanRelevantResearch #3Rs #AnimalResearch #AlternativeMethods #Organoids #OrganOnChip #InVitroModels #TranslationalResearch #Bioengineering #ResearchInnovation #NC3Rs #ImperialCollegeLondon Imperial Organoid Facility Imperial Medicine Animal Free Research UK
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Meet our biochips Choosing the right biochip format is an important step in building a meaningful organ-on-chip model. Different research questions require different microenvironments — from compartmentalized co-cultures and 3D spheroid models to integrated sensor readouts for barrier integrity or oxygen monitoring. In this carousel, we introduce the dynamic42 biochip portfolio and show how each format supports specific experimental needs: 🔹 2-Channel Biochip 🔹 2-Channel Precious Biochip 🔹 3-Channel Biochip 🔹 Spheroid Biochip 🔹 TEER-Sensor Biochip 🔹 O₂-Sensor Biochip Whether you are studying barrier function, working with valuable samples, developing complex co-cultures, or monitoring key physiological parameters — the right biochip design helps shape the right model. 👉 Swipe through the carousel to explore which biochip could support your next organ-on-chip project. #OrganOnChip #Biochips #MicrophysiologicalSystems #InVitroModels #CellCulture #DrugDevelopment #Toxicology #mps
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In part 2 of Minds Behind Organ-on-Chip season 2, we continue our video interview series spotlighting researchers advancing MPS and organ-on-chip technologies. We visited Nicole Engert in Jena, where she works in the AG Mosig research group at University Hospital Jena in Germany. She spoke with us about her research on a stem cell-derived gut-on-chip technology to elucidate human norovirus infections. Over the coming weeks, we’ll share more interviews with researchers developing organ models across a range of fields and highlighting the exciting work behind them. Follow us and don’t miss a single video! #organonchip #mps