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Developmental Epidemiology

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lightbulbAbout this topic
Developmental Epidemiology is the study of the distribution and determinants of health-related states or events in populations, focusing on the developmental stages of individuals. It examines how biological, environmental, and social factors influence health outcomes across the lifespan, particularly during critical periods of growth and development.
lightbulbAbout this topic
Developmental Epidemiology is the study of the distribution and determinants of health-related states or events in populations, focusing on the developmental stages of individuals. It examines how biological, environmental, and social factors influence health outcomes across the lifespan, particularly during critical periods of growth and development.

Key research themes

1. How does prenatal and early life environment influence the risk of non-communicable diseases across the lifespan?

This research theme investigates the role of early developmental factors, particularly prenatal and perinatal exposures, in shaping susceptibility to chronic diseases such as diabetes, cardiovascular diseases, obesity, and mental health disorders later in life. It integrates epidemiological data, mechanistic insights, and animal models to elucidate the concept of Developmental Origins of Health and Disease (DOHaD), emphasizing the impact of maternal nutrition, intrauterine environment, and epigenetic modifications on offspring health. Understanding these early life influences is critical for shifting prevention focus from adult risk factor management to primordial and primary prevention targeting early developmental stages.

Key finding: This paper elucidates how both maternal undernutrition and overnutrition influence offspring body composition and metabolic risk, demonstrating the 'thin-fat' phenotype in Indian newborns with disproportionately higher... Read more
Key finding: Through evidence including the Dutch famine studies and twin research, this review confirms that adverse prenatal environments (nutritional restriction or overnutrition) induce disproportionate fetal growth and organ... Read more
Key finding: This article advances the DOHaD paradigm by focusing on environmental and occupational hazards alongside nutritional imbalances as early-life stressors disrupting development. It identifies epigenetic reprogramming,... Read more
Key finding: This review identifies family-level psychosocial and socioeconomic stressors (e.g., domestic violence, parental mental health issues, substance abuse) as critical environmental risk factors adversely affecting child... Read more

2. What are the methods and frameworks for assessing early childhood development and neurodevelopmental vulnerabilities in epidemiological studies?

This theme explores conceptual frameworks, epidemiological methodologies, and longitudinal cohort designs tailored to assess neurodevelopmental outcomes from infancy through adolescence. It spans analytic approaches such as latent class analysis and cumulative risk indices to capture multifactorial and dynamic developmental vulnerabilities. These frameworks facilitate identification of at-risk populations early, enabling targeted interventions and contributing to more standardized assessment approaches internationally.

Key finding: The study established a prospective longitudinal cohort, enrolling pregnant women before 24 weeks of amenorrhea, with detailed measurement of maternal exposures and repeated child neurodevelopmental assessments up to 8 years.... Read more
Key finding: Using latent class analysis on large population data (~67,000 children), this study identified distinct patterns of early developmental vulnerabilities, linking these classes with demographic and environmental exposures,... Read more
Key finding: This paper proposes a structured framework categorizing neuropsychological outcomes at multiple levels (e.g., cognitive, behavioral domains) to harmonize terminology and facilitate coherent assessment strategies across... Read more
Key finding: The study advances regression analytic methods to optimize weighting of cumulative risk indices encompassing environmental and genetic factors impacting neurodevelopment. By demonstrating that weighted composite indices... Read more

3. How do acute and chronic environmental and social stressors during epidemics and pandemics impact child growth and development?

This area focuses on the developmental and mental health consequences of epidemic-related social restrictions, parental stress, and infectious exposures on children and adolescents. It assesses mechanisms linking adverse childhood experiences (ACEs), toxic stress, and neurodevelopmental outcomes in the context of global health crises such as COVID-19. Findings here underscore the complex interplay of biological, psychosocial, and environmental stressors across developmental windows, informing strategies for mitigation and resilience promotion.

Key finding: This ongoing international prospective longitudinal study tests the hypothesis that prenatal SARS-CoV-2 exposure increases risk for atypical neurodevelopment through the maternal immune response and cytokine-mediated... Read more
Key finding: The study establishes a quantifiable dose-response relationship wherein each additional maternal adverse childhood experience (ACE) correlates with an 18% increased risk of suspected developmental delay at 24 months,... Read more

All papers in Developmental Epidemiology

With research suggesting increasing incidence of pediatric neurodevelopmental disorders, questions regarding etiology continue to be raised. Neurodevelopmental function tests have been used in epidemiology studies to evaluate... more
Developmental trauma disorder (DTD) and posttraumatic stress disorder (PTSD) have been found to have both shared and unique traumatic antecedents. The present study was an independent replication, with the DTD Structured Interview and the... more
Your article is protected by copyright and all rights are held exclusively by Springer Science +Business Media New York. This e-offprint is for personal use only and shall not be selfarchived in electronic repositories. If you wish to... more
Following on a similar effort last year, five senior researchers have each selected two articles that they believe represent the best violence research published in 2012 and, like members of the panel that selected 2011 articles, once... more
Youth raised by a caregiver experiencing harmful effects associated with alcohol use may experience multiple types of adversity. While the association between caregiver problem drinking and child maltreatment are well established, there... more
The obligation to protect children is defined by law. However, there is fragility in identifying actual or potential situations that jeopardize their development. This review aims to identify the family risk factors that jeopardize child... more
Research links high youth exposure to community violence (ECV) with negative health consequences, and the World Health Organization recommends ECV as a new adverse childhood experience (ACE) category. The current study is among the first... more
Maternal smoking during pregnancy increases the risk of obesity in the offspring. Not much is known about the associations with other measures of body composition. We assessed the associations of maternal smoking during pregnancy with the... more
Trauma exposure is common during childhood and adolescence and is associated with youth emotional and behavioral problems. The present study adds to the current literature on trauma exposure among adolescent clinical populations by... more
Child sexual exploitation (CSE) has a long and ignominious history and continues to emotionally and physically injure and adversely alter the development, sense of self, relationships, and life course of millions of children and... more
The obligation to protect children is defined by law. However, there is fragility in identifying actual or potential situations that jeopardize their development. This review aims to identify the family risk factors that jeopardize child... more
Violence exposure in adolescence can disrupt ongoing adjustment, yet few studies have examined potential mechanisms that can explain these effects. Using data from the National Longitudinal Study of Adolescent to Adult Health, we examined... more
This article looks at a psychotherapist's lessons learned at the intersection of trauma and antisocial behavior in 20 years of working in American prisons, forensic hospitals, and trauma centers. Typically, posttraumatic stress disorder... more
Though childhood sexualized assault (CSA) increases risk for varied psychological difficulties, no single condition, syndrome, or set of difficulties is reliably associated with such experiences. CSA likely disrupts or impairs normal... more
Background: Mental health diseases are responsible for 16% of the global burden of disease in adolescents. Identifying the main determinants of these disorders in this age group can direct public and political efforts aimed at their... more
Developmental trauma disorder (DTD) and posttraumatic stress disorder (PTSD) have been found to have both shared and unique traumatic antecedents. The present study was an independent replication, with the DTD Structured Interview and the... more
and I were so struck and pleased by one aspect of the second issue that we felt it was worth explicitly noting. What caught our attention was the diversity of material in this issue. Without plan or design, we found that the range and... more
There has been approximately 1.5 million service members who have spent service time in Iraq, of which about 500,000 have served two tours of combat (Whitlock, 2008 as cited by Huebner, Mancini, Bowen, & Orthner, 2009). Given that... more
Background: Evidence suggests that childhood is an important critical period for adult mental health outcomes. Most studies evaluating childhood factors use cross-sectional data, limiting our understanding of life course factors... more
by Azia Berhe and 
1 more
Developmental trauma disorder (DTD) is not a formally recognised as a diagnosis in the current diagnostic systems. There has been a push for its inclusion by child psychiatrists and psychologists within the past decade. There are a... more
This dissertation consists of two studies designed to broaden our understanding of the impact of complex trauma on symptom profiles and outcomes of children in the child welfare system through the lenses of gender, development, and... more
Case studies are an important venue for reporting clinical processes relevant to clinical care, research agendas, and interprofessional collaboration. Clinical Practice in Pediatric Psychology (CPPP) is actively soliciting case studies to... more
In middle childhood and adolescence, the most rapidly developing brain areas are those responsible for three core features of "executive functioning" necessary for autonomous functioning and engagement in relationships. These... more
BACKGROUND: Research indicates that childhood trauma is a pervasive, global, healthcare crisis with a majority (68%) of children having experienced exposure to traumatic events. 1 Youth who have multiple exposures to violence or... more
The accuracy of the Content should not be relied upon and should be independently verified with primary sources of information. Taylor and Francis shall not be liable for any losses, actions, claims, proceedings, demands, costs, expenses,... more
Patterns of trauma exposure and symptoms were examined in a sample of 16,212 children in Illinois child welfare. Data were collected on trauma histories, child and caregiver needs and strengths, and analyzed in light of the proposed... more
Research links high youth exposure to community violence (ECV) with negative health consequences, and the World Health Organization recommends ECV as a new adverse childhood experience (ACE) category. The current study is among the first... more
for primary prevention and clinical approaches to disrupt risk pathways and to optimize long-term outcomes.
As the university environment can present unique challenges, it is important to look at the ways in which childhood trauma can impact student resilience, especially in non-Western contexts. The present study examines the relationship... more
Two divergent areas of study have focused on the experiences of grief, i.e., bereavement, and on trauma and its aftermath. The grief literature has its foundations in psychodynamic and relational theories, and thus treatment modalities... more
Adolescence is a unique developmental period in which youth are at heightened risk for violence perpetration and victimization, both of which can adversely affect the course of normal psychosocial development and health across the life... more
Background and Objectives. Adverse childhood experiences include stressful and potentially traumatic events associated with a higher risk of long-term behavioral problems and chronic illnesses. In this study, we had estimated the... more
Objective: This study determined whether county-level social determinants of health and adverse childhood experiences (ACE) were associated with emotional support and health-related quality of life (HRQOL) in adulthood. This study... more
Exposure to Adverse Childhood Experiences (ACEs) is associated with a host of harmful outcomes, including increased risk for cancer. A scoping review was conducted to gain a better understanding of how ACEs have been studied in... more
Background: The impact of adverse childhood experiences (ACEs) significantly determines whether an individual will be functional or dysfunctional in adulthood. Aims: The current study examines the prevalence and the socio-demographic... more
Compared to many parts of the world, there has been little research in Pacific Island nations into the effects of Adverse Childhood Experiences (ACEs) on adult health. This is a significant gap for local evidence-based child protection.... more
This study was designed to test the feasibility and child clinical outcomes for group-based trauma-focused cognitive behavior therapy (TF-CBT) for orphaned children in Tanzania. There were 64 children with at least mild symptoms of grief... more
Objective: Mass casualty events pose dilemmas for community clinicians, often challenging their existing clinical toolkits. However, few clinicians were trained to be experts in explaining the unfolding events to the community, creating... more
The purpose of the present study was to examine the evidence for the complex trauma definition in children, utilizing children's self-reported trauma-related symptoms. Two hundred and twelve children (ages 8–16) exposed to a traumatic... more
Objective: To better understand the role earlier stressful environments have in predicting functional somatic symptoms (FSS) in late adolescence, this study explores the effect the occurrence of earlier changes in family dynamics and... more
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