Key research themes
1. How does prenatal and early life environment influence the risk of non-communicable diseases across the lifespan?
This research theme investigates the role of early developmental factors, particularly prenatal and perinatal exposures, in shaping susceptibility to chronic diseases such as diabetes, cardiovascular diseases, obesity, and mental health disorders later in life. It integrates epidemiological data, mechanistic insights, and animal models to elucidate the concept of Developmental Origins of Health and Disease (DOHaD), emphasizing the impact of maternal nutrition, intrauterine environment, and epigenetic modifications on offspring health. Understanding these early life influences is critical for shifting prevention focus from adult risk factor management to primordial and primary prevention targeting early developmental stages.
2. What are the methods and frameworks for assessing early childhood development and neurodevelopmental vulnerabilities in epidemiological studies?
This theme explores conceptual frameworks, epidemiological methodologies, and longitudinal cohort designs tailored to assess neurodevelopmental outcomes from infancy through adolescence. It spans analytic approaches such as latent class analysis and cumulative risk indices to capture multifactorial and dynamic developmental vulnerabilities. These frameworks facilitate identification of at-risk populations early, enabling targeted interventions and contributing to more standardized assessment approaches internationally.
3. How do acute and chronic environmental and social stressors during epidemics and pandemics impact child growth and development?
This area focuses on the developmental and mental health consequences of epidemic-related social restrictions, parental stress, and infectious exposures on children and adolescents. It assesses mechanisms linking adverse childhood experiences (ACEs), toxic stress, and neurodevelopmental outcomes in the context of global health crises such as COVID-19. Findings here underscore the complex interplay of biological, psychosocial, and environmental stressors across developmental windows, informing strategies for mitigation and resilience promotion.




































