MassChallenge’s cover photo
MassChallenge

MassChallenge

Venture Capital and Private Equity Principals

Boston, Massachusetts 45,321 followers

Solving humanity's hardest challenges is possible when the world's best founders and industry leaders work together.

About us

Headquartered in the United States with eight locations worldwide, MassChallenge exist because the future depends on radically reimagining support for those with the grit to solve humanity’s hardest challenges.

Website
http://www.masschallenge.org
Industry
Venture Capital and Private Equity Principals
Company size
51-200 employees
Headquarters
Boston, Massachusetts
Type
Nonprofit
Founded
2009
Specialties
Startups, Business Competition, Accelerator Program, Entrepreneurship, Founders, HealthTech, FinTech, ClimateTech, Security and Resiliency, and Sustainable Food Systems

Locations

Employees at MassChallenge

Updates

  • Thanks to Lucia Maffei and the Boston Business Journal for covering our launch of Breakthrough Bio. This new global program connects promising biotech and medtech startups from Israel and Taiwan with the investors, industry leaders, regulators, and mentors they need to accelerate commercialization in the U.S. Read the story below. 👇

    The word is out! #Boston is the #biotech capital of the world. We're building the on-ramp. MassChallenge just launched #BreakthroughBio: a six-month hybrid program bringing 10 biotech and medtech startups each from Israel and Taiwan into the U.S. market, with real access to the investors, regulators, mentors and industry partners who move the needle. Proud to be doing this alongside our inaugural partners, the Israel Innovation Authority and Taiwan's Development Center for Biotechnology. And a big thank you to Lucia Maffei at the Boston Business Journal for a terrific piece capturing what we're building. This isn't just a program. It's the start of a movement: the best and brightest from across nations, together in one ecosystem. https://lnkd.in/g52_SRtG

  • Thanks to the Boston Business Journal for highlighting YES/Boston. Great ideas move further, faster when founders have the right support around them, and we're proud to help build that alongside World Economic Forum, Amazon Web Services (AWS), Citi, and Deloitte.

    View organization page for Boston Business Journal

    40,862 followers

    An innovation cohort in Boston will be testing new ways to use food as medicine. Yes/Boston, an initiative spun out of the World Economic Forum in February 2026 that is being led locally by MassChallenge, named 12 founders to be part of its first food systems and health innovation cohort. Reporter Maren Halpin

  • "They hand you a map, drawn by the people who know the terrain." That's one of our favorite lines from Brittany Hume Charm's reflections on YES/Boston's Reverse Pitch Day. Great startups don't fail because they lack talent. They stall because breakthrough ideas don't succeed on their own. Founders have to navigate complex systems, build the right relationships, and earn the trust of institutions that don't move overnight. That's where MassChallenge does its best work. Reverse Pitch Day wasn't another networking event. It was an opportunity for founders to hear directly from the healthcare leaders, government agencies, nonprofits, and industry partners shaping the systems they're working to change, and to begin building the relationships that can help accelerate adoption. Brittany captures the conversations that made the day so memorable below. 👇

    Imagine being an entrepreneur, walking into a room of major stakeholders in your target market. They know who you are, they believe you have something they need, and they are ready to tell you exactly how to work with them. They hand you a map, drawn by the people who know the terrain. That is what happened last week for the 12 food-as-health innovators in Yes/Boston's inaugural cohort, part of UpLink – World Economic Forum's Yes/Cities urban transformation initiative. Day Two of our kickoff brought the Commonwealth of Massachusetts, the City of Boston, The Greater Boston Food Bank, major payers and health systems, and other business and nonprofit stakeholders to sit down with these founders. They arrived--and sparks flew. ThriveLink (helping families enroll in government benefits and social services) spoke directly with Massachusetts Department Of Transitional Assistance—the agency overseeing SNAP and looking for better ways to support enrollment as documentation requirements rise. Matriark Foods connected with Mass General Brigham to explore adding Matriark's food products made from upcycled surplus vegetables into its hospital food service operations, improving nutrition and flavor while reducing waste. Family Dinner (seeking to link its regional network of farmers to Boston-area school cafeterias) pulled up a chair to get the counsel of Jen Faigel of CommonWealth Kitchen, whose marinara and tikka masala sauces are launching in 89 school districts across Massachusetts this fall. FoodCopia - Inventory Software & More for Food Banks got to ask The Greater Boston Food Bank directly about the tech capabilities and needs of the hundreds of pantries it services across eastern Massachusetts. Health In Her HUE raised to Blue Cross Blue Shield of Massachusetts' innovation and community health leaders the potential to replicate its existing partnership with BCBS of Minnesota to connect women of color with culturally competent care. MassChallenge is this program's local accelerator. But last week made clear that the real accelerant—the secret sauce of speed and success—will be this engaged, connected network. Thank you to everyone who showed up to make it possible, including our co-sponsors Amazon Web Services (AWS), Citi, and Deloitte. And if you want to be in this amazing room next time, reach out—we'd love to have a conversation about joining our coalition.

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  • MassChallenge reposted this

    Meet our #founders! 🎥 We're excited to launch a new interview series featuring #startups from the MassChallenge Switzerland cohort. First up is Soil Next, sharing how they're helping improve #soil health, the problem they're solving, and their experience so far at MassChallenge.👇 🌱 Soil Next makes the invisible visible. While billions are invested in regenerative #agriculture, there is still no scalable way to verify it's working. Using commercial robotic microscope and proprietary AI, we reveal the soil food web, delivering insights on soil health, water retention, benchmarks, and tailored recommendations, all in < 48h. We provide the evidence needed to prove #regeneration works.

  • View organization page for MassChallenge

    45,321 followers

    Great science is happening everywhere.   Access to the investors, industry relationships, and commercialization expertise that bring breakthrough discoveries to patients isn't.   Today, we're changing that.   We're proud to launch Breakthrough Bio, a new global program giving high-potential biotech and medtech startups a direct path into the U.S. life sciences ecosystem.   Because the world's best science deserves the world's fastest path to market.   We're honored to launch the inaugural program with the Israel Innovation Authority and Taiwan's Development Center for Biotechnology, with additional global partnerships to come.   Learn more: https://bit.ly/4vVxOAk   #Biotech #MedTech #Commercialization #GlobalInnovation #MassChallenge #BreakthroughBio

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  • During Sail Boston, we had the privilege of welcoming Captain Kristopher Ensley, Commanding Officer of the USCGC Eagle, to MassChallenge for an afternoon of conversation on leadership, innovation, and the people behind breakthrough ideas.   The big idea Captain Ensley shared was that the hardest missions require people with character, resilience, and the ability to lead through uncertainty.   Throughout the afternoon, he returned to that message in different ways, describing the timeless lessons learned on the decks of Eagle as lessons of "resilience, leadership, character, and fundamental competence." He spoke about preparing officers who will be ready "when the mission demands courage in the face of uncertainty," reminding us that tomorrow's leaders need "character... and resilience."   That message resonated because, while the missions may be different, we see many of those same qualities in the founders we support.   The entrepreneurs in the MassChallenge community are tackling the world's most complex challenges. They're developing technologies that strengthen healthcare, food systems, manufacturing, national security, climate resilience, and the blue economy. The path from breakthrough idea to real-world impact is rarely straightforward. It requires technical excellence, perseverance, and the willingness to keep moving when the path ahead is uncertain.   That's why MassChallenge exists.   We believe the future depends on those rare humans willing to take on the most complex challenges. Our role is to help those extraordinary founders succeed by surrounding them with the customers, partners, mentors, investors, and networks that accelerate commercialization and increase the likelihood that breakthrough technologies reach the people and industries that need them most.   Captain Ensley's perspective was a powerful reminder that while technology continues to evolve, success has always depended on the people willing to take on difficult problems and the communities that prepare and support them.   Thank you to Captain Kristopher Ensley for sharing your perspective, and special thanks to co-founders Kim Gavin and Robert J. McGurrin from BLUEiQ for demonstrating how innovation is shaping the future of maritime security, and to everyone who joined us for an afternoon of thoughtful conversation about leadership, innovation, and the future of the blue economy. #MassChallenge #Innovation #MaritimeInnovation #BlueTech #USCGCEagle

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  • The best startup ecosystems are built by people who are willing to share what they've learned. We're excited to see our own Kelly Becker joining an incredible lineup of founders, operators, and investors at Startup Boston Week to share lessons from supporting early-stage innovators. We'll see you there! Register at: https://lnkd.in/dQUAQ8em #StartupBostonWeek #MassChallenge #StartupEcosystem #Innovation #Boston

    View organization page for Startup Boston

    20,217 followers

    The best startup advice rarely comes from people who've only studied entrepreneurship. It comes from the people building companies, solving hard problems, leading teams, and figuring things out in real time. That's why every year at Startup Boston Week, founders, operators, investors, and ecosystem leaders volunteer their time to share what they've learned with the community. 🎟️ Registration is completely free: https://lnkd.in/dQUAQ8em Here's a small preview of the incredible speakers joining us this September: 🎤 Taylor Caforio — CEO & Co-Founder, Haven AI 🎤 Pavana Rotti, PhD — CEO & Co-Founder, Nervoid Inc 🎤 Dolphy Fernandes — Customer Success Engineering Leader 🎤 Immanuel John — Group Product Manager, AI & IoT, Komar Industries 🎤 Kelly Becker — Senior Director of Programs, MassChallenge 🎤 Ratnam S. — Founder & CEO, LabOps Inc. 🎤 Sandra Perez Botero — Programs Director, EforAll & Founder, Isense Innovation 🎤 Rob Blaine — CEO & Founder, TNT Whether you're building AI products, commercializing breakthrough research, scaling customer success, growing an early-stage company, or expanding your startup network, this group has been there. They're now giving back by sharing the lessons they've learned so you can avoid a few mistakes of your own. That's what Startup Boston Week has always been about: bringing together people who are actively building startups to help the next generation of founders, operators, and innovators build a little smarter. Join us September 14–18 for the 10th Annual Startup Boston Week, featuring 100+ sessions, 250+ speakers, and five days dedicated to New England's startup community. 🎟️ Registration is completely free: https://lnkd.in/dQUAQ8em

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  • Are you attending DallasMeetup at Texas Live! on August 13? We're excited to share that our own Lauren Adegoke, MS, Senior Manager of Programs at MassChallenge, will be making her debut as DallasMeetup's latest Featured Networker! If you're a founder, investor, corporate innovator, or ecosystem partner attending the event, we'd love to connect. 🔗 Register here: https://luma.com/b6618q2k #DallasMeetup #MassChallenge #StartupEcosystem #Innovation

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  • Massachusetts has world-class arts and culture sitting alongside a world-class innovation economy. Most regions would trade a lot for that combination, which has tremendous potential when truly working together. Over the past year, MassChallenge and Mass Cultural Council, the Commonwealth's state arts agency, have been exploring this creative advantage, talking with leaders across the arts, economic development, technology, and the nonprofit sector about how the intersection of creative practice and economic can strengthen the way founders and institutions build. Now we want to hear from more of you. We put together a short survey with three quick questions: 1. Where do you see the biggest potential in connecting the cultural sector with entrepreneurship? 2. How should those connections happen, whether through policy, messaging, convenings, or partnerships? 3. Would you want to be part of this work going forward? It takes just a few minutes, and your input will directly shape where we take this next. 👉 Share your perspective here: https://lnkd.in/eXdzEshA #CreativeEconomy #Innovation #MassChallenge #Massachusetts #PowerOfCulture #mapoli 

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  • View organization page for MassChallenge

    45,321 followers

    Massachusetts climatetech startups: Applications are open for the 2026 AcceliCITY Mass Climate Tech Challenge. Our friends at Leading Cities are helping founders build connections with municipalities, access deployment support, receive certified B2G training, connect with investors, and compete for up to $175,000 in non-dilutive funding. Applications close August 20. Apply here: https://lnkd.in/g_mQuEBF 🔗

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